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Dual-Locked Polymeric STING Nano-Agonist/Sonosensitizer Augments Spatiotemporally Controlled Cancer Sono-Immunotherapy

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The stimulator of interferon genes (STING) pathway is a central target in cancer immunotherapy, but current STING agonist therapies lack precision control, leading to suboptimal therapeutic outcomes and systematic adverse effects. Herein, we engineered a dual-... ...