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An RGD motif on SARS-CoV-2 Spike induces TGF-β signaling and downregulates interferon

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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein mediates canonical cell entry via ACE2 and has also been implicated as an activator of a diverse range of signaling pathways. Here, we present evidence that the RGD (Arg-Gly-Asp... ...