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Expression of Oct3/4 isoforms and its association with the risk of relapse in acute lymphoblastic leukemia

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Oct3/4 is a transcription factor that maintains the stemness of both embryonic and adult stem cells. The Oct3/4 gene produces three isoforms: namely, Oct3/4A, Oct3/4B and Oct3/4B1. Increased Oct3/4 expression is associated with lower survival rates and chemore... ...