A novel intron variant is associated with emerging pfdhps mutant haplotypes in West and Central African Plasmodium falciparum
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Sulfadoxine-pyrimethamine plays a key role in Plasmodium falciparum chemoprevention across Africa, yet the protective efficacy of SP is undermined by mutations conferring resistance in the genes encoding dihydrofolate reductase (pfdhfr) and dihydropteroate syn... ...