TGF-β inhibitor SB431542 suppresses SARS-CoV-2 replication through multistep inhibition
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The coronavirus disease 2019 (COVID-19) pandemic highlighted the critical need for broad-spectrum antivirals with high resistance barriers. Here, we demonstrate that SB431542, a selective TGF-β receptor I (ALK5) inhibitor, exhibits potent antiviral activity a... ...