Camptothecin, a topoisomerase I inhibitor, impedes productive herpes simplex virus type 1 infection
{{output}}
Herpes simplex virus type 1 (HSV-1) is a double-stranded DNA virus that infects most of the human population. We previously found that cellular topoisomerase I (TOP1) associates with the HSV-1 genome throughout infection. TOP1 relieves topological stress on DN... ...
