Effect of dietary zinc supplementation on the gastrointestinal microbiome and host gene expression in the Shank3B-/- mouse model of autism spectrum disorder
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Shank gene variants are implicated in ~1% of people with autism, and mice lacking Shank3 exhibit autism-like behaviours. Zinc deficiency and gastrointestinal problems can be common among people with autism, and zinc is a key element required for SHANK protein ... ...