African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylation
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African swine fever virus (ASFV) infection induces oxidative stress and produces oxidative DNA damage bases, including 8-oxoguanine (8-oxoG). It is essential to promptly repair these damages to maintain genome stability. The enzyme 8-oxoguanine DNA glycosylase... ...