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Engineering a Viscosity-Gated Dual-Rotor Probe for Comprehensive Mapping of Lipid Droplet Heterogeneity

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Small, metabolically active lipid droplets (LDs) with elevated core viscosity play pivotal roles in lipid metabolism and disease yet remain underexplored due to their transient nature and the limitations of conventional probes. Here, we report YTT-Z, a viscosi... ...