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Evaluation of the Safety of A Novel Anti-HER2 Immunotoxin Containing Modified Fragment of Pseudomonas Exotoxin in BALB/C Mice

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Background: Human epidermal growth factor-2 (HER-2) receptors are overexpressed in some malignancies like breast cancer. Previously, we constructed a novel anti-HER immunotoxin, scFv-PE35KDEL, containing modified fragments of Pse... ...