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Serum IL-1ra Is Associated with but Has No Genetic Link to Type 1 Diabetes

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Interleukin-1 antagonism is a proposed biomarker and potential therapy for the delay and/or treatment of type 1 diabetes (T1D). We evaluated the role of circulating interleukin-1 receptor antagonist (IL-1ra) in a prospectively monitored cohort of T1D patients.... ...