Lithium-doped calcium silicate scaffolds-activated M2-polarized macrophage-derived miR-145-5p-riched extracellular vesicles to enhance osteoimmunomodulation for accelerating bone regeneration
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Bone healing is intricately associated with dynamic macrophage polarization. Modulating macrophages toward the M2 phenotype has emerged as a promising strategy in bone tissue engineering. Calcium silicate, known for its superior osteoconductivity, is widely us... ...