Combination of hydroxycitric acid and capsaicin regulates IRS-1/AMPK-mTOR-SREBP-1c Axis/NLRP3-NF-κB/Nrf-2-ARE signaling pathways to ameliorate the two-hit process in high-fat diet-induced hepatic steatosis
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Metabolic (Dysfunction) Associated Steatotic Liver Disease (MASLD) is a complex metabolic condition, the progression of which toward steatohepatitis can be explained by the 'two-hit' hypothesis: the first hit involves lipid accumulation, and the second hit i... ...