PolyA-Bridged Aptamer for Label-Free Electrochemical Aptasensors: Comparable Performance to Thiol-Terminated Aptamer but with Sharply Reduced Cost
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Thiol-terminated aptamers (SH-Apt) enable Au-S self-assembly on Au electrodes but face great challenges due to expensive thiol modification and laborious disulfide cleavage steps. Poly adenine (PolyA)-mediated aptamers offer a simpler and cost-effective altern... ...
