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An In Vivo Fluorescence Image Analysis Tool for Esterase Activity Quantification in Daphnia: Using Calcein AM in Ecotoxicological Studies

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There is an increasing need for new approach methodologies (NAMs) to generate relevant ecotoxicological data. This study demonstrates the strengths of calcein AM, a highly sensitive fluorescent stain for esterase activity, in an automated image-based multiwell... ...