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SARS-CoV-2 Nsp15 endoribonuclease subverts host defenses to enhance viral fitness in lung cells

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Coronaviruses encode nonstructural protein 15 (Nsp15), a conserved endoribonuclease (EndoU) known to suppress host antiviral responses. It is imperative to understand the role of Nsp15/EndoU during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) i... ...