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Are Solid Particles Ready for Prime-Time Proteomics?

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We evaluate the performance of nonporous C-18 stationary phases in high-speed proteomics workflows. We employed two commercially available sub-2 μm nonporous particle (NPP) materials, ODS-IIIE (1.5 μm) and SOLAD (1.0 μm), to fabricate analytical columns usi... ...