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Engineered MEVs for photoreceptor-targeted delivery of USP25 to alleviate diabetic retinopathy

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Diabetic retinopathy (DR) is the major cause of vision decline in adults worldwide. Photoreceptor loss is considered a main pathogenesis of retinal dysfunction in DR. Recently, mesenchymal stem cell-derived extracellular vesicles (MEVs) treatment has been cons... ...