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Exploring Conformational Transitions in Biased and Balanced Ligand Binding of GLP-1R

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The glucagon-like peptide-1 receptor (GLP-1R), which belongs to the class B1 G protein-coupled receptor (GPCR) family, is an important target for treatment of metabolic disorders, including type 2 diabetes and obesity. The growing interest in GLP-1R-based ther... ...