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Deficiency of interleukin-1 receptor antagonist aggravates Citrobacter rodentium infection in mice

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The interleukin-1 receptor (IL-1R) plays an important role in mediating the inflammatory responses against pathogens. However, it is not clear whether a sustained IL-1R signaling following the loss of its endogenous inhibitor, IL-1R antagonist (IL-1RA), could ... ...