Nonequilibrium Capillary Electrophoresis of Equilibrium Mixtures (NECEEM)-Enabled Mechanistic Analysis of Cooperative Binding: Application to C-Reactive Protein-SOMAmer Complexes
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Understanding cooperative binding is essential for characterizing interactions between multimeric proteins and their ligands, because biological function often depends on binding stoichiometry or allosteric regulation. Detailed characterization of cooperativit... ...
