Blasticidin S Biosynthesis Involves a Unique Interplay between a Radical SAM Dehydratase, a Transaminase and an ATP-Grasp Ligase in Order to Avoid a Futile Cycle
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Blasticidin S is a peptidyl nucleoside that blocks protein synthesis in prokaryotes and eukaryotes. It is widely used in molecular biology as a selection agent. Despite its utility, the biosynthetic origin of its 2',3'-unsaturated-4'-aminoacyl-4'-deoxyhexo... ...
