Activation of the HPV16 late promoter by viral E2 and cellular BRD4 and ZC3H4 proteins
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High-risk human papillomaviruses (HPV), particularly HPV16, are major causes of anogenital and oropharyngeal cancers. The HPV late promoter, P670 in the case of HPV16, is activated upon host cell differentiation and drives the expression of viral capsid protei... ...