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FluMag-SELEX derived specific individual aptamers can fluorescently label the ageing immanent protein-crosslinker glucosepane in diabetic mouse tissues

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Nowadays, aptamers have transitioned into valuable antibody alternatives. We present the first anti-glucosepane aptamer targeting a key glycation product linked to aging and diabetes. Glu3, with high specificity and affinity, enabled the first-ever direct, flu... ...