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Cis-resveratrol blocks crystal-induced NLRP3 inflammasome activation via the TRPV4-Ca²⁺-phagocytosis-ROS axis

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Background: Inflammation is a vital biological defense mechanism, yet uncontrolled or prolonged inflammation can cause tissue damage. The NLRP3 inflammasome, a central component of innate immunity, drives inflammation by activati... ...