Beneficial APD-shortening effects, but deleterious negative inotropism of IKs-activator Docosahexaenoyl glycine (DHA-gly) in long QT syndrome type 2
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Background and aims: Loss-of-function mutations in KCNQ1 and KCNH2 (α-subunits of the slow delayed IKs and rapid delayed IKr-conducting repolarising K+ channels) lead to long QT syndrome type 1 (LQT1) and 2 (LQT2), respectively.... ...
