A laminin α4-CD8+ T cell axis shapes the prognostic impact of macrophages and regulatory T cells in early-stage colorectal cancer
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The crossing of the endothelial basement membranes (BMs) is a limiting step for leukocyte diapedesis. Heterotrimeric laminins (LMs) containing α4- and α5-chains are major BM components with opposite effects on transendothelial migration. Here, we examined wh... ...
