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Synergistic effect of piperine on curcumin in cisplatin-induced nephrotoxicity through DNA fragmentation and cytokines gene expressions

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Cisplatin (Cis) is an anticancer drug commonly used to treat solid tumors. However, because of its nephrotoxicity, its use is limited. Our goal was to evaluate the effects of curcumin (Cur) and piperine (Pip) administered separately versus combined on Cis-indu... ...