TET1 functions as a tumor suppressor in lung adenocarcinoma through epigenetic remodeling and immune modulation
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Background: Ten-Eleven Translocation (TET1-3) dioxygenases oxidize 5-methylcytosine (5mC) in DNA to generate 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC), initiating DNA demethylation. Sin... ...
