Proteome and secretome profiling of the melanoma-induced transition towards immune incompetent dendritic cells reveals enhanced IDO1, cathepsin, and legumain activity
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Dendritic cells (DCs) are professional antigen-presenting cells endowed with the capacity to initiate strong antitumor immune responses. This function is critical for effective DC-based immunotherapies but is often hampered by tumor-derived immunosuppressive f... ...
