Alpha-dystroglycan receptor signaling likely influences basement membrane laminin α2 mediated pathology in the stria vascularis of Alport mice
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We previously demonstrated that endothelin A receptor (ETAR) signaling plays a major role in regulating strial pathology in the COL4A3 knockout mouse model for Alport syndrome. Blocking the receptor prevented accumulation of extracellular matrix (ECM) in the s... ...
