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Rational Design and Relative Bioperformance of High Drug Load Grazoprevir Amorphous Nanoparticle Formulations

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This work looked to determine if a rationally designed amorphous nanoparticle formulation of Grazoprevir (GZP) could provide a benefit over its amorphous dispersion formulation by either enabling superior bioperformance or accessing higher drug loadings. GZP-e... ...