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Limitations of boronate affinity chromatography for the specific enrichment of fructose-derived early glycation products in protein analytics

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Protein glycation, or non-enzymatic glycosylation, refers to the reaction of reducing sugars with amino groups in proteins to form Amadori and Heyns products for aldoses (e.g., glucose) and ketoses (e.g., fructose), respectively. While Amadori peptides have be... ...