Nasal and systemic immune responses correlate with viral shedding after influenza challenge in people with complex preexisting immunity
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Each year in the United States, ~50% of adults ≥18 years old are vaccinated against influenza viruses, with protective efficacy averaging 40.5% over the past 20 years. To model annual seasonal influenza, a cohort of 74 adults, who were unscreened for preexist... ...