The cleavage of indinavir sulfate: synthesis and characterization of a cis-1-amino-2-indanol salt
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The HIV-1 protease inhibitor indinavir sulfate was cleaved via a one-pot reflux synthesis using 1-propanol, yielding the salt bis(2-hydroxy-2,3-dihydro-1H-inden-1-aminium) sulfate, 2C9H12NO+·SO42-. Single-crystal X-ray diffraction (SC-XRD) revealed that the s... ...
