PAK1 Signaling in Cancer: Multifaceted Roles and Therapeutic Implications
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PAK1, a serine-threonine kinase, acts as an effector of Rac, Ras, and CDC42, which are pivotal in oncogenic signaling pathways. Its involvement spans critical cellular processes like cell cycle regulation, angiogenesis, and metastasis. PAK1 also influences the... ...
