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TOB Proteins Repress Translation via the CCR4-NOT Deadenylase Complex Independent of Deadenylation

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Transducer of ErbB2 (TOB) proteins have been shown to promote mRNA decay through interactions with the CCR4-NOT complex and poly(A)-binding protein (PABP). While their role in deadenylation-mediated mRNA degradation is well established, their potential functio... ...