Smiles-Truce Cascades Enable Heteroaryl Cyclopropane and Sultine Synthesis
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We describe a triple C─C bond cascade process for heteroaryl cyclopropane synthesis, through the reaction of vinyl sulfonium salts and sulfones under mild conditions. An initial conjugate addition (C─C bond 1) sets up a Smiles-Truce rearrangement (C─C bond ... ...