Structural and functional studies of rabbit SAMD9 reveal a distinct tRNase module that underlies the antiviral activity
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Human SAMD9 and SAMD9L (collectively SAMD9/9L) are large cytoplasmic proteins with antiviral and antiproliferative activities, recently shown to regulate protein synthesis by specifically depleting phenylalanine tRNA (tRNAPhe). The enzymatic activity of human ... ...
