Artesunate modulates the tumor microenvironment via STAT1/IRF1-mediated TAM repolarization and T cell activation in non-small cell lung cancer
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Background: In non-small cell lung cancer (NSCLC), M2-polarized tumor-associated macrophages (TAMs) induce T cell dysfunction and correlate with poor clinical outcomes. Recent studies have demonstrated that artesunate (AS) enhanc... ...