Annona muricata Graviola Induces Apoptosis in Two Osteosarcoma Cell Lines and Downregulates the Cytokines IL-6 and TGFβ1 Which Are Implicated in Tumour Growth and Metastasis
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BackgroundOsteosarcoma (OS) is an aggressive bone tumour which affects mostly young children. Despite advances in chemotherapy regimens there is still high fatality and cure rates remain low. Annona muricata Graviola (GR) is a tropical fruit bearing tree whose... ...