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Synergy of triazolyl substituents at C1 and C3 of galactose for high-affinity and selective galectin-4C inhibition

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Galectins are a family of carbohydrate-recognising proteins involved in regulation of cell adhesion and cell signaling, leading to roles in e.g. cancer progression, fibrosis, and ulcerative colitis. Glycomimetic galectin inhibitors based on different molecular... ...