Patient-derived TXNIP-deficient primary cells exhibit NRF2 activation linked to upregulation of glyoxalase 1 (GLO1)
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Thioredoxin-interacting protein (TXNIP) plays a pivotal role in cellular redox regulation and has been implicated in various pathological conditions, including oxidative stress, inflammation and metabolic disorders including diabetes. In this study, we investi... ...