Synthesis of sensitive oligodeoxynucleotides containing acylated cytosine, adenine, and guanine nucleobases
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The synthesis of oligodeoxynucleotides (ODNs) containing the base-labile N 6-acetyladenosine (6acA), N 2-acetylguanosine (2acG), and N4-methyoxycarbonyldeoxycytidine (4mcC), as well as up to four N 4-acetyldeoxycytidine (4acC) modifications is described. The 1... ...