Glycoconjugated Metallohelices Eliminate Cancer Stem-Like Cells via Modulating G-Quadruplex Surrounding Transcriptional Start Site of Sox2 Gene
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As an important pluripotency transcription factor, Sox2 plays key roles in the stemness maintenance of cancer stem-like cells (CSCs). Here, we found that a highly conserved G-rich region surrounding transcriptional start sites (TSSs) of Sox2 gene can form G-qu... ...
