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A putative PIWIL/piRNA-OTX2 network: An emerging model for epigenetic regulation of cancer stemness in retinoblastoma

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Recent findings underscore the critical role of PIWIL/piRNA pathways in cancer, extending their known functions beyond reproductive biology. Retinoblastoma (RB), a rare pediatric retinal tumor, is primarily driven by RB1 gene loss but also involves significant... ...