BIRC3 deficiency blocks the ubiquitination and degradation of GOT2 to impede antitumor immune responses in lung squamous cell carcinoma
{{output}}
In lung squamous cell carcinoma (LUSC), the proportion of exhausted CD8+ T cells is considerably higher than in lung adenocarcinoma (LUAD). The exhaustion of CD8+ T cells is responsible for the failure of immunotherapies, as terminally exhausted CD8+ T cells d... ...
