Hyperpolarized [1-13C] pyruvate MRSI reveals a diet-dependent metabolic shift in ZSF1 rats
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We evaluated altered cardiac metabolism in Zucker Spontaneously Hypertensive Fatty (ZSF1) rats fed an isocaloric high-fat diet versus normal chow using hyperpolarized (HP) [1-13C]pyruvate MR spectroscopic imaging (MRSI). This technique exploits remarkable sign... ...
