B cells drive CCR5+CD4+ tissue-resident memory T cell cytotoxicity via IL-15Rα-IL-15 signaling in primary biliary cholangitis
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Background & aims: IL-15Rα mediates immune responses by binding and trans-presenting IL-15 to tissue-resident memory T (TRM) cells, enabling sustained activation. Given the pivotal role of IL-15Rα/IL-15 signaling in autoimmune ... ...
