Crosstalk between the aryl hydrocarbon receptor and hypoxia-inducible factor 1α pathways in human islet models
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Background: We previously showed that 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD - a persistent organic pollutant) activates the aryl hydrocarbon receptor (AHR) in pancreatic islets. The AHR is known to crosstalk with hypoxia-indu... ...
